UQCC2 and CEACAM5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		UQCC2	CEACAM5
Description		ubiquinol-cytochrome c reductase complex assembly factor 2	CEA cell adhesion molecule 5
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Nuclear Body Mitochondrial Nucleoid	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Anchored Component Of Membrane Extracellular Exosome Integral Component Of External Side Of Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding GPI Anchor Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Regulation Of Insulin Secretion Positive Regulation Of Mitochondrial Translation Regulation Of Skeletal Muscle Cell Differentiation	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Myotube Differentiation Homotypic Cell-cell Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of Anoikis
Pathways			Post-translational modification: synthesis of GPI-anchored proteins Cell surface interactions at the vascular wall
Drugs			Labetuzumab S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Diseases
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gait speed in old age ( 28077804) Hodgkin's lymphoma ( 30194254)	Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		15 interacting genes: CDKN2D CEACAM5 EXOC8 GNG13 GRB2 HSPB1 MKRN3 MRFAP1 NRDE2 RABGAP1L SNAP25 TRAPPC2 TRAPPC2B TXN2 ZNF765	7 interacting genes: CEACAM1 CEACAM6 DISP3 EWSR1 HNRNPM IMPDH2 UQCC2
Entrez ID		84300	1048
HPRD ID		12847	00274
Ensembl ID		ENSG00000137288	ENSG00000105388
Uniprot IDs		Q9BRT2	A0A024R0K5 P06731 Q53G30
PDB IDs			1E07 2QSQ 2QST 2VER
Enriched GO Terms of Interacting Partners?
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