CEACAM5 and UQCC2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CEACAM5	UQCC2
Description		CEA cell adhesion molecule 5	ubiquinol-cytochrome c reductase complex assembly factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Anchored Component Of Membrane Extracellular Exosome Integral Component Of External Side Of Plasma Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Nuclear Body Mitochondrial Nucleoid
	Molecular Function	Protein Binding GPI Anchor Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Myotube Differentiation Homotypic Cell-cell Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of Anoikis	Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Regulation Of Insulin Secretion Positive Regulation Of Mitochondrial Translation Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Post-translational modification: synthesis of GPI-anchored proteins Cell surface interactions at the vascular wall
Drugs		Labetuzumab S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Serum carcinoembryonic antigen levels ( 31666285)	Asthma and attention deficit hyperactivity disorder ( 31619474) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gait speed in old age ( 28077804) Hodgkin's lymphoma ( 30194254)
Interacting Genes		7 interacting genes: CEACAM1 CEACAM6 DISP3 EWSR1 HNRNPM IMPDH2 UQCC2	15 interacting genes: CDKN2D CEACAM5 EXOC8 GNG13 GRB2 HSPB1 MKRN3 MRFAP1 NRDE2 RABGAP1L SNAP25 TRAPPC2 TRAPPC2B TXN2 ZNF765
Entrez ID		1048	84300
HPRD ID		00274	12847
Ensembl ID		ENSG00000105388	ENSG00000137288
Uniprot IDs		A0A024R0K5 P06731 Q53G30	Q9BRT2
PDB IDs		1E07 2QSQ 2QST 2VER
Enriched GO Terms of Interacting Partners?
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