ING5 and APLP1

Number of citations of the paper that reports this interaction (PubMedID 15383276)
151

Data Source:
BioGRID (two hybrid)

		ING5	APLP1
Description		inhibitor of growth family member 5	amyloid beta precursor like protein 1
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex	Basement Membrane Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding
	Biological Process	DNA Replication Regulation Of Transcription, DNA-templated Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Apoptotic Signaling Pathway	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Extracellular Matrix Organization Forebrain Development Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs			Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)	Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		45 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1	43 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 ERBB2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24
Entrez ID		84289	333
HPRD ID		16348	00102
Ensembl ID		ENSG00000168395	ENSG00000105290
Uniprot IDs		A0A1B0GW41 Q8WYH8	P51693
PDB IDs		3C6W 5ME8 5MTO	3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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