FLYWCH1 and LHX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FLYWCH1	LHX2
Description		FLYWCH-type zinc finger 1	LIM homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body	Chromatin Nucleus
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process		Neural Tube Closure Hair Follicle Development Regulation Of Transcription By RNA Polymerase II Axon Guidance Mesoderm Development Dorsal/ventral Pattern Formation Olfactory Bulb Development Telencephalon Regionalization Cerebral Cortex Development Neuron Differentiation Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Axon Extension Negative Regulation Of Neurogenesis Retina Development In Camera-type Eye Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Post bronchodilator FEV1 ( 26634245)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Blond vs. brown/black hair color ( 30531825) Depression ( 29700475) Hair color ( 29662168) Mercury levels ( 26025379) Post-traumatic stress disorder ( 25456346) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Waist circumference ( 23966867)
Interacting Genes		14 interacting genes: CCDC125 CCDC136 ERBB3 GMCL1 GOLGA6L9 HOOK2 HSF2BP KIFC3 LHX2 MTUS2 PICK1 PPP1R16B SETDB1 TRAF2	29 interacting genes: ANKS1A ARHGAP32 BEND2 CITED2 DNMT3L ENG FLYWCH1 HOMER3 HOXC8 KHK LDB1 LGALSL LNX1 LONRF1 MORF4L1 MORN3 MSX1 OSMR PAX6 POU4F2 PPIL1 RLIM TCEANC TCP11L1 TLK1 TRAPPC2L UBTFL1 ZFP42 ZNF511
Entrez ID		84256	9355
HPRD ID		13222	04786
Ensembl ID		ENSG00000059122	ENSG00000106689
Uniprot IDs		Q4VC44	B3KNJ5 P50458
PDB IDs		2RPR
Enriched GO Terms of Interacting Partners?
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