KAT8 and SRY

		KAT8	SRY
Description		lysine acetyltransferase 8	sex determining region Y
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Kinetochore Nucleus Nucleoplasm Nuclear Matrix MLL1 Complex MSL Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Acetyltransferase Activity Enzyme Binding Methylated Histone Binding Histone Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Metal Ion Binding Histone Acetyltransferase Activity (H4-K16 Specific)	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Calmodulin Binding Transcription Factor Binding
	Biological Process	Regulation Of Autophagy Histone Acetylation Myeloid Cell Differentiation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Sex Differentiation Anatomical Structure Morphogenesis Positive Regulation Of Gene Expression Cell Differentiation Male Sex Determination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Male Gonad Development
Pathways		HATs acetylate histones	Deactivation of the beta-catenin transactivating complex Transcriptional regulation of testis differentiation
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 25673413) Family history of Alzheimer's disease ( 30617256) Parkinson's disease ( 28892059) Triglyceride levels ( 32154731)
Interacting Genes		22 interacting genes: ATM BAZ1B BAZ2A CFAP119 CLEC4A FOXP3 H4C1 KMT2A LIMS1 NFATC2IP ORAI3 PAF1 PLAU PRRT2 RABEP2 RNF2 SLC7A5P1 SRY SSTR5 TP53 TP53BP1 ZNF764	8 interacting genes: AR EP300 HDAC3 KAT8 KPNB1 SLC9A3R2 SMAD3 ZNF208
Entrez ID		84148	6736
HPRD ID		11381	08364
Ensembl ID		ENSG00000103510	ENSG00000184895
Uniprot IDs		Q9H7Z6	A7WPU8 Q05066
PDB IDs		2GIV 2PQ8 2Y0M 3QAH 3TOA 3TOB 4DNC 5H43 5J8C 5J8F 5WCI 6BA2 6BA4 6CT2 6OIN 6OIO 6OIP 6OIQ 6OIR 6OWH 6OWI 6PD8 6PD9 6PDA 6PDB 6PDC 6PDD 6PDE 6PDF 6PDG 7CMR	1HRY 1HRZ 1J46 1J47 2GZK 6EDB
Enriched GO Terms of Interacting Partners?
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