KATNAL1 and KLC4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		KATNAL1	KLC4
Description		katanin catalytic subunit A1 like 1	kinesin light chain 4
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Microtubule Microtubule Cytoskeleton	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	Protein Binding ATP Binding Microtubule Binding Microtubule-severing ATPase Activity Isomerase Activity Identical Protein Binding	Protein Binding
	Biological Process	Spermatogenesis Microtubule Severing
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Blood osmolality (transformed sodium) ( 28360221) Fat distribution (HIV) ( 21897333) Male-pattern baldness ( 27182965) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928) Refractive error ( 32231278) Type 2 diabetes ( 31049640)	Hemoglobin levels ( 32327693)
Interacting Genes		17 interacting genes: ASCC2 BYSL C1orf109 CEP57L1 COX17 CTNNA3 GCC1 GUCA1A IQUB KATNBL1 KLC4 MEOX2 PGAM2 PITPNC1 SIAH1 VPS4B ZNF69	34 interacting genes: ABI3 AKAP9 APP CASK CEP57 CEP57L1 COIL DDX6 KATNAL1 KLC2 KPNA2 KRT13 KRT15 KRT16 KRT31 KRT33B KRT34 MEOX2 NDEL1 NECAB2 PCM1 PDE4DIP PKP2 PRC1 RBM14 SERTAD1 SLC16A9 TADA2A TCTE1 TSC1 USHBP1 YWHAE YWHAZ ZNF343
Entrez ID		84056	89953
HPRD ID		13753	13932
Ensembl ID		ENSG00000102781	ENSG00000137171
Uniprot IDs		A0A024RDP8 B3KUK7 Q9BW62	A0A024RCZ8 Q9NSK0
PDB IDs		6B5C
Enriched GO Terms of Interacting Partners?
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