KATNAL1 and ASCC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KATNAL1	ASCC2
Description		katanin catalytic subunit A1 like 1	activating signal cointegrator 1 complex subunit 2
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GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Microtubule Microtubule Cytoskeleton	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	Protein Binding ATP Binding Microtubule Binding Microtubule-severing ATPase Activity Isomerase Activity Identical Protein Binding	Protein Binding Ubiquitin Binding
	Biological Process	Spermatogenesis Microtubule Severing	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways			ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Blood osmolality (transformed sodium) ( 28360221) Fat distribution (HIV) ( 21897333) Male-pattern baldness ( 27182965) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928) Refractive error ( 32231278) Type 2 diabetes ( 31049640)	Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		17 interacting genes: ASCC2 BYSL C1orf109 CEP57L1 COX17 CTNNA3 GCC1 GUCA1A IQUB KATNBL1 KLC4 MEOX2 PGAM2 PITPNC1 SIAH1 VPS4B ZNF69	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		84056	84164
HPRD ID		13753	16515
Ensembl ID		ENSG00000102781	ENSG00000100325
Uniprot IDs		A0A024RDP8 B3KUK7 Q9BW62	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs		6B5C	2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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