OBSCN and DNAJB5

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		OBSCN	DNAJB5
Description		obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	DnaJ heat shock protein family (Hsp40) member B5
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Nuclear Body Myofibril Z Disc M Band Sarcolemma	Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Calmodulin Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Structural Constituent Of Muscle Phosphatidylinositol-5-phosphate Binding Ankyrin Binding Titin Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding Cell Adhesion Molecule Binding Phosphatidylinositol-4-phosphate Binding Protein Serine Kinase Activity	Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Protein Phosphorylation Protein Localization To M-band Sarcomere Organization Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Cell-cell Adhesion	Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163) Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433) PR interval ( 30046033 32439900)	Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		8 interacting genes: ANK1 ANK2 BRCA1 CALM1 DNAJB5 MTDH MYH2 TTN	12 interacting genes: ANK2 CACNA1A MRFAP1 MYBPC1 NOCT OBSCN SIGMAR1 SMAD2 SMAD3 TAF1 TBPL2 TTN
Entrez ID		84033	25822
HPRD ID		10551	07106
Ensembl ID		ENSG00000154358	ENSG00000137094
Uniprot IDs		A6NGQ3 Q5VST9	O75953
PDB IDs		1V1C 2CR6 2DKU 2DM7 2E7B 2EDF 2EDH 2EDL 2EDQ 2EDR 2EDT 2EDW 2ENY 2EO1 2GQH 2MWC 2N56 2YZ8 4C4K 4RSV 4UOW 5TZM 6MG9
Enriched GO Terms of Interacting Partners?
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