PIP5K1A and PIP5KL1

Number of citations of the paper that reports this interaction (PubMedID 14701839)
9

Data Source:
HPRD (in vivo)

		PIP5K1A	PIP5KL1
Description		phosphatidylinositol-4-phosphate 5-kinase type 1 alpha	phosphatidylinositol-4-phosphate 5-kinase like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Focal Adhesion Nuclear Speck Lamellipodium Ruffle Membrane	Cytosol Membrane Cell Projection
	Molecular Function	1-phosphatidylinositol-3-phosphate 5-kinase Activity Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Kinase Binding 1-phosphatidylinositol-5-kinase Activity Phosphatidylinositol-3,4-bisphosphate 5-kinase Activity	ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity
	Biological Process	Glycerophospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phagocytosis Signal Transduction Phospholipid Biosynthetic Process Fibroblast Migration Regulation Of Phosphatidylinositol 3-kinase Signaling Phosphorylation Cell Migration Keratinocyte Differentiation Actin Cytoskeleton Reorganization Phosphatidylinositol Phosphate Biosynthetic Process Focal Adhesion Assembly Cell Chemotaxis Protein Localization To Plasma Membrane Activation Of GTPase Activity Ruffle Assembly	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Mitochondrial Membrane Potential Phosphorylation Negative Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		Synthesis of PIPs at the plasma membrane PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Body mass index ( 26426971)
Interacting Genes		16 interacting genes: APP ARF1 ARF5 ARF6 BTK CADPS CASP3 KRAS MIR140 MIR34B NEDD4 PIP5KL1 PLD1 PLD2 RHOU TEC	2 interacting genes: PIP5K1A PIP5K1B
Entrez ID		8394	138429
HPRD ID		04470	15139
Ensembl ID		ENSG00000143398	ENSG00000167103
Uniprot IDs		A6PW57 Q99755	Q5T9C9
PDB IDs
Enriched GO Terms of Interacting Partners?
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