KRTAP9-2 and GNE

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		KRTAP9-2	GNE
Description		keratin associated protein 9-2	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Cytoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein Binding ATP Binding UDP-N-acetylglucosamine 2-epimerase Activity N-acylmannosamine Kinase Activity Metal Ion Binding
	Biological Process		N-acetylglucosamine Biosynthetic Process UDP-N-acetylglucosamine Metabolic Process N-acetylneuraminate Metabolic Process Cell Adhesion Carbohydrate Phosphorylation
Pathways		Keratinization	Sialic acid metabolism Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2
Drugs
Diseases
GWAS			Bipolar disorder (inflammation and infection response interaction) ( 25781172) Bisphosphonate-associated atypical femoral fracture ( 31006051)
Interacting Genes		142 interacting genes: ADAM12 ADAMTSL4 AGXT AQP1 ARFGAP1 ATG9A AXIN2 C22orf39 CARD10 CATSPER1 CCDC28A CERK CHRD CNNM3 COL8A1 CRCT1 CREB5 CTRC CYP21A2 CYSRT1 DMRT3 DOCK2 FAM76B FBXO34 GATA1 GEMIN4 GLRX3 GNE GNG13 GUCD1 HAPLN2 HOXA1 ITGB4 JOSD1 KLHL38 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP17-1 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-3 KRTAP9-4 KRTAP9-8 LBX1 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MGAT5B NBPF19 NOTCH2NLA NR1D2 NR4A3 NTAQ1 NUFIP2 OTX1 P2RY6 P3H3 PDE9A PHLDA1 PIGS PLLP PLSCR1 POTEB3 POU4F2 PRKAB2 PRKAG1 PTPMT1 RCHY1 RNF31 RNF8 SDC3 SHFL SLC13A5 SLC39A7 SMCP SPATA3 SPATA8 SPRY1 SPRY2 SUMO1P1 TFAP2D TMEM190 TMSB10 TRIM54 TSPAN4 TYRO3 VGLL3 ZDHHC1 ZDHHC17 ZNF20 ZNF575 ZNF696	66 interacting genes: ADAMTSL4 C22orf39 CFP CRMP1 CYSRT1 ECM1 EGFL7 GRN GTPBP3 HOXA1 KIAA1549 KPRP KRT31 KRT34 KRT40 KRT83 KRT85 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP13-2 KRTAP13-3 KRTAP17-1 KRTAP19-2 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-4 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 MDFI MGAT5B NBPF19 NID2 NOTCH2NLA PLA2G10 PRICKLE4 RIF1 SIGMAR1 SPRY1 SPRY2 SPRY3 SSC4D TRIM27 TRIM42 TRIP6 TSPAN4 VWC2 WDR83 WWOX ZBTB16
Entrez ID		83899	10020
HPRD ID		13949	04825
Ensembl ID		ENSG00000239886	ENSG00000159921
Uniprot IDs		Q9BYQ4	Q9Y223
PDB IDs			2YHW 2YHY 2YI1 3EO3 4ZHT
Enriched GO Terms of Interacting Partners?
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