ATG10 and ATG12

Number of citations of the paper that reports this interaction (PubMedID 12482611)
18

Data Source:
HPRD (in vivo, in vitro)

		ATG10	ATG12
Description		autophagy related 10	autophagy related 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex
	Molecular Function	Protein Binding Atg12 Transferase Activity	Protein Binding
	Biological Process	Protein Lipidation Autophagy ER Overload Response Protein Transport Macroautophagy Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Autophagy Of Nucleus
Pathways		Macroautophagy Macroautophagy	Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Airway imaging phenotypes ( 26030696) Breast cancer ( 25751625 29059683) Carotid intima media thickness (mean) ( 31801372) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels in HIV infection ( 33109212) LDL cholesterol levels in HIV infection ( 33109212)	Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		5 interacting genes: ATG12 ATG5 ATG7 DNAI1 IRGM	16 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2 SRP19
Entrez ID		83734	9140
HPRD ID		16497	08496
Ensembl ID		ENSG00000152348	ENSG00000145782
Uniprot IDs		Q9H0Y0	O94817
PDB IDs			4GDK 4GDL 4NAW
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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