ATG12 and SERTAD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATG12	SERTAD2
Description		autophagy related 12	SERTA domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding Transcription Regulator Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Autophagy Of Nucleus	Negative Regulation Of Cell Growth Chromatin-mediated Maintenance Of Transcription
Pathways		Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)	Antisaccade task score ( 31596458) Apolipoprotein B levels ( 32203549) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Visceral fat ( 22589738)
Interacting Genes		16 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2 SRP19	28 interacting genes: AP2B1 ATG12 C1orf109 CDC7 CEP68 CKS1B CREBBP CTNNA3 E2F1 ESPNL HELLS IGFN1 KAT2B KAT5 PARVG PIK3R3 PLA2G6 PRKAB2 REL STRA8 SUPT7L TFDP1 TNS2 TRIM28 XPO1 ZNF524 ZNF581 ZSCAN22
Entrez ID		9140	9792
HPRD ID		08496	18040
Ensembl ID		ENSG00000145782	ENSG00000179833
Uniprot IDs		O94817	Q14140
PDB IDs		4GDK 4GDL 4NAW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?