DRC3 and SMCR8

		DRC3	SMCR8
Description		dynein regulatory complex subunit 3	SMCR8-C9orf72 complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axoneme Motile Cilium	Chromatin Nucleoplasm Cytoplasm Guanyl-nucleotide Exchange Factor Complex Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding
	Biological Process		Negative Regulation Of Protein Kinase Activity Autophagy Regulation Of Autophagy Negative Regulation Of Gene Expression Negative Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Positive Regulation Of Autophagosome Maturation Negative Regulation Of Autophagosome Assembly Regulation Of TORC1 Signaling
Pathways
Drugs
Diseases
GWAS			Change in neurofilament light levels ( 31295725) Diastolic blood pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		12 interacting genes: EIF3E ELAC2 FUNDC2 GID4 MFHAS1 PLAGL1 SMCR8 SOD2 SPECC1 ZNF250 ZNF287 ZNF624	6 interacting genes: ATG13 C9orf72 DRC3 TBK1 TOM1L2 ULK1
Entrez ID		83450	140775
HPRD ID		13181	18075
Ensembl ID		ENSG00000171962	ENSG00000176994
Uniprot IDs		B3KSC6 Q9H069	Q8TEV9
PDB IDs			6LT0 6V4U
Enriched GO Terms of Interacting Partners?
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