SMCR8 and DRC3

		SMCR8	DRC3
Description		SMCR8-C9orf72 complex subunit	dynein regulatory complex subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytoplasm Guanyl-nucleotide Exchange Factor Complex Atg1/ULK1 Kinase Complex	Cytoplasm Axoneme Motile Cilium
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Autophagy Regulation Of Autophagy Negative Regulation Of Gene Expression Negative Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Positive Regulation Of Autophagosome Maturation Negative Regulation Of Autophagosome Assembly Regulation Of TORC1 Signaling
Pathways
Drugs
Diseases
GWAS		Change in neurofilament light levels ( 31295725) Diastolic blood pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		6 interacting genes: ATG13 C9orf72 DRC3 TBK1 TOM1L2 ULK1	12 interacting genes: EIF3E ELAC2 FUNDC2 GID4 MFHAS1 PLAGL1 SMCR8 SOD2 SPECC1 ZNF250 ZNF287 ZNF624
Entrez ID		140775	83450
HPRD ID		18075	13181
Ensembl ID		ENSG00000176994	ENSG00000171962
Uniprot IDs		Q8TEV9	B3KSC6 Q9H069
PDB IDs		6LT0 6V4U
Enriched GO Terms of Interacting Partners?
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