TRRAP and PYGO2

Number of citations of the paper that reports this interaction (PubMedID 20937768)
28

Data Source:
BioGRID (pull down)

		TRRAP	PYGO2
Description		transformation/transcription domain associated protein	pygopus family PHD finger 2
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex	Nucleoplasm Beta-catenin-TCF Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding Kinase Activity	Chromatin Binding Protein Binding Histone Acetyltransferase Regulator Activity Histone Binding Metal Ion Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Histone Acetylation Histone Deubiquitination Histone H4 Acetylation Histone H2A Acetylation	Kidney Development Lens Development In Camera-type Eye Spermatid Nucleus Differentiation Brain Development Mammary Gland Development Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Histone Acetylation Positive Regulation Of Chromatin Binding Developmental Growth Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Canonical Wnt Signaling Pathway
Pathways		Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		19 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MMS22L MRGBP MYC PYGO2 SKP1 TCF3	7 interacting genes: AKT1 BCL9 DCAF1 KAT2A NF2 SUPT3H TRRAP
Entrez ID		8295	90780
HPRD ID		04310	06065
Ensembl ID		ENSG00000196367	ENSG00000163348
Uniprot IDs		Q9Y4A5	Q5T170 Q9BRQ0
PDB IDs			2XB1 4UP0 4UP5
Enriched GO Terms of Interacting Partners?
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