LLGL1 and USP11

Number of citations of the paper that reports this interaction (PubMedID 26919101)
14

Data Source:
BioGRID (affinity chromatography technology, pull down)

		LLGL1	USP11
Description		LLGL scribble cell polarity complex component 1	ubiquitin specific peptidase 11
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Cis Cisterna Cytoplasm Cytoskeleton Plasma Membrane Axon Cortical Actin Cytoskeleton Early Endosome Membrane Trans-Golgi Network Membrane	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	GTPase Activator Activity Structural Molecule Activity Protein Binding Protein Kinase Binding Myosin II Binding	Transcription Corepressor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Regulation Of Notch Signaling Pathway Cortical Actin Cytoskeleton Organization Regulation Of Establishment Or Maintenance Of Cell Polarity Regulation Of Protein Secretion Regulation Of Catalytic Activity Establishment Of Spindle Orientation Protein-containing Complex Assembly	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination
Pathways			Association of TriC/CCT with target proteins during biosynthesis Ub-specific processing proteases
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: ACD AGTR1 CACNA1A CD46 STX4 USP11	22 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 NONO PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC
Entrez ID		3996	8237
HPRD ID		02982	02081
Ensembl ID		ENSG00000131899	ENSG00000102226
Uniprot IDs		Q15334	B4DGK3 P51784
PDB IDs			4MEL 5OK6
Enriched GO Terms of Interacting Partners?
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