NCOA3 and IQCK

Number of citations of the paper that reports this interaction (PubMedID 21577200)
75

Data Source:
BioGRID (two hybrid)

		NCOA3	IQCK
Description		nuclear receptor coactivator 3	IQ motif containing K
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome
	Molecular Function	RNA Polymerase II Complex Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Nuclear Receptor Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding Protein Dimerization Activity Protein N-terminus Binding Disordered Domain Specific Binding
	Biological Process	Histone Acetylation Cellular Response To Hormone Stimulus Receptor Transactivation Cell Dedifferentiation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estradiol Stimulus Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Division
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Activation of anterior HOX genes in hindbrain development during early embryogenesis MAPK6/MAPK4 signaling Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Osteoarthritis (hip) ( 23989986) Response to treatment for acute lymphoblastic leukemia ( 19176441)	Alzheimer's disease (late onset) ( 30820047) Body mass index ( 20935630 29273807) Diastolic blood pressure ( 31134134) Diastolic blood pressure (education interaction) ( 31134134) Waist circumference ( 28552196) Waist-hip ratio ( 28552196)
Interacting Genes		82 interacting genes: ABL1 ANKRD11 AR ARNT2 ATAD2 BABAM2 BMP6 BMP7 BRCA1 CCND1 CDKN3 CHUK CREBBP CSNK1E DCTN6 DDX17 DDX5 E2F1 EP300 ESR1 ESR2 ESRRA ESRRB ETV1 FOS GSK3B GTF2B H3-4 H4-16 HNF1A IKBKB IKBKG IQCK JUN KAT2B MAPK1 MAPK14 MAPK8 MMS19 MN1 MRTFA MRTFB NCOR1 NCOR2 NKX2-1 NPAS2 NR0B2 NR1H2 NR1H3 NR1I2 NR1I3 NR2F1 NR3C1 NR4A1 NR5A2 PGR PIN1 PPARA PPARD PPARG PRKCZ PRMT1 PSMB9 PSME3 RARA RARB RARG RELA RXRA RXRB SLC22A2 SMARCE1 SPOP SUFU SUMO1 TBP THRB TP53 TP53BP1 VDR YWHAH YWHAQ	1 interacting genes: NCOA3
Entrez ID		8202	124152
HPRD ID		03570	11340
Ensembl ID		ENSG00000124151	ENSG00000174628
Uniprot IDs		Q59EE8 Q9Y6Q9	B4DXE1 B4E1V3 Q8N0W5
PDB IDs		1KBH 3L3X 3L3Z 6ES7 6SQC
Enriched GO Terms of Interacting Partners?
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