SYMPK and MIR107

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		SYMPK	MIR107
Description		symplekin scaffold protein	microRNA 107
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex Cytoskeleton Plasma Membrane Bicellular Tight Junction Nuclear Body Nuclear Stress Granule	Extracellular Space Neuronal Cell Body Extracellular Vesicle
	Molecular Function	Protein Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	MRNA Polyadenylation Cell Adhesion Negative Regulation Of Protein Binding Positive Regulation Of Protein Dephosphorylation	Cellular Response To Insulin Stimulus Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Gluconeogenesis Negative Regulation Of Glucose Import Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Necroptotic Process Cellular Response To Hydrogen Peroxide Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Asthma ( 31959851) Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Colon cancer ( 28295283) Colorectal cancer ( 28295283) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494)
Interacting Genes		45 interacting genes: CSTF2 HSF1 HTT MIR1-2 MIR107 MIR128-2 MIR138-2 MIR155 MIR15B MIR16-2 MIR17 MIR18A MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200C MIR20B MIR21 MIR214 MIR25 MIR29A MIR34A MIR363 MIR7-2 MIR9-1 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7D MIRLET7E MIRLET7G MIRLET7I RIN3 SUMO2 TOP1 TRIM55 TRIM63 UBE2I YBX3	83 interacting genes: AIMP1 AIMP2 AQR C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM17 RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		8189	406901
HPRD ID		09090
Ensembl ID		ENSG00000125755	ENSG00000198997
Uniprot IDs		A0A024R0R6 Q92797
PDB IDs		3O2Q 3O2S 3O2T 3ODR 3ODS 4H3H 4H3K 6V4X
Enriched GO Terms of Interacting Partners?
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