MED25 and OXER1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MED25	OXER1
Description		mediator complex subunit 25	oxoeicosanoid receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Mediator Complex	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transcription Coactivator Binding Protein Binding Transcription Factor Binding Retinoic Acid Receptor Binding Retinoid X Receptor Binding	G Protein-coupled Receptor Activity Protein Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Positive Regulation Of Mediator Complex Assembly	Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Eicosanoid ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood trace element (Se levels) ( 23720494)	Attention deficit hyperactivity disorder ( 18821565) Breastfeeding duration ( 25475840) Hyperactive-impulsive symptoms ( 18821565)
Interacting Genes		37 interacting genes: CDK8 CREBBP CTDP1 CYSRT1 ESRP1 EYA2 FAM168B HCFC1 HGS KLHL12 KRTAP6-1 KRTAP6-3 LASP1 MED1 MED15 MED6 MED8 MED9 NCKIPSD NR3C1 ODAM OXER1 PEF1 PLEKHB2 RARA RORB RUSC1 RXRA SERTAD3 SREBF1 STAT5B TFG THRA TLE5 USP54 WWOX WWP2	46 interacting genes: ANAPC11 ARRB2 ASB13 ATG9A CCNK CRYBA2 EFCAB3 ESRP1 FOXH1 HNF1B HNRNPH1 INTS11 JMJD7 KRTAP12-3 KRTAP19-5 KRTAP4-2 KRTAP5-6 KRTAP6-3 LASP1 MED25 NCS1 NEK8 NOC4L OTX1 PLSCR4 PRKAB2 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 RAMAC RBFOX2 RECK RNF208 RNF38 RNF44 TFG TLE5 TP53BP1 VGLL3 ZBTB32 ZC3H10 ZIC1
Entrez ID		81857	165140
HPRD ID		14380	17812
Ensembl ID		ENSG00000104973	ENSG00000162881
Uniprot IDs		Q71SY5	Q8TDS5
PDB IDs		2KY6 2L23 2L6U 2XNF
Enriched GO Terms of Interacting Partners?
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