UNC93B1 and BEST2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UNC93B1	BEST2
Description		unc-93 homolog B1, TLR signaling regulator	bestrophin 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome	Plasma Membrane Cilium Chloride Channel Complex
	Molecular Function	Protein Binding Toll-like Receptor Binding	Molecular_function Chloride Channel Activity Protein Binding
	Biological Process	Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus	Chloride Transport Sensory Perception Of Smell Biological_process Membrane Depolarization
Pathways		Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE	Stimuli-sensing channels
Drugs
Diseases
GWAS		Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237	16 interacting genes: CLDN10 COMT CYB561 DNAJC30 EFNA5 FXYD3 GPR25 MALL MFSD5 PNLIPRP1 RFT1 SLC66A2 TMEM128 TMEM60 UNC93B1 UPK1B
Entrez ID		81622	54831
HPRD ID		12191	09548
Ensembl ID		ENSG00000110057	ENSG00000039987
Uniprot IDs		Q9H1C4	Q8NFU1
PDB IDs		7C76 7CYN
Enriched GO Terms of Interacting Partners?
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