B9D2 and PLEKHG2

		B9D2	PLEKHG2
Description		B9 domain containing 2	pleckstrin homology and RhoGEF domain containing G2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Membrane MKS Complex Ciliary Basal Body	Cytosol
	Molecular Function	Protein Binding Gamma-tubulin Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Cilium Assembly	Regulation Of Actin Filament Polymerization Regulation Of Catalytic Activity
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	NRAGE signals death through JNK G alpha (12/13) signalling events CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 32469254 29212778) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)
Interacting Genes		15 interacting genes: ALKBH7 CCDC97 CCNP CEACAM21 CNFN P4HA3 PLEKHA7 PLEKHG2 PPP1R32 QARS1 SPAG8 TLX3 VPS25 YIF1B ZNF574	9 interacting genes: ACTN3 APP B9D2 CDC42 GNG2 PIN1 RAC1 RHOA XRN1
Entrez ID		80776	64857
HPRD ID		14613	15148
Ensembl ID		ENSG00000123810	ENSG00000090924
Uniprot IDs		Q9BPU9	Q9H7P9
PDB IDs
Enriched GO Terms of Interacting Partners?
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