PLEKHG2 and B9D2

		PLEKHG2	B9D2
Description		pleckstrin homology and RhoGEF domain containing G2	B9 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Centrosome Cytosol Membrane MKS Complex Ciliary Basal Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Regulation Of Actin Filament Polymerization Regulation Of Catalytic Activity	Cilium Assembly
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events CDC42 GTPase cycle RAC1 GTPase cycle	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 32469254 29212778) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)
Interacting Genes		9 interacting genes: ACTN3 APP B9D2 CDC42 GNG2 PIN1 RAC1 RHOA XRN1	15 interacting genes: ALKBH7 CCDC97 CCNP CEACAM21 CNFN P4HA3 PLEKHA7 PLEKHG2 PPP1R32 QARS1 SPAG8 TLX3 VPS25 YIF1B ZNF574
Entrez ID		64857	80776
HPRD ID		15148	14613
Ensembl ID		ENSG00000090924	ENSG00000123810
Uniprot IDs		Q9H7P9	Q9BPU9
PDB IDs
Enriched GO Terms of Interacting Partners?
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