CEP63 and BFSP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CEP63	BFSP2
Description		centrosomal protein 63	beaded filament structural protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Centriole Cytosol	Intermediate Filament Plasma Membrane Cell Cortex
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding
	Biological Process	DNA Damage Checkpoint Signaling Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation	Visual Perception Intermediate Filament Organization Cell Maturation Response To Stimulus Lens Fiber Cell Development
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Height ( 18391952) Hip circumference adjusted for BMI ( 34021172) Late-onset Alzheimer's disease ( 27770636) Neurocognitive impairment in HIV-1 infection (dichotomous) ( 28447399) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		67 interacting genes: ALOX5 ARFIP2 ARNT2 BFSP2 BRPF1 CAMKK2 CAPN7 CCDC14 CCDC187 CCHCR1 CCNI CDK1 CEP57 CEP57L1 CWF19L2 DAXX DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 FEM1C GSE1 HAUS1 HGS INTS6L KANK2 KXD1 MACF1 MBIP MNS1 NCOR2 NDC80 NDEL1 NXT2 PCNX4 PIBF1 POLR3C PPP1R13B PPP4R1 RCOR3 ROGDI SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 STAG1 SYNE1 SYT17 TBC1D15 TBC1D22B TSG101 TSGA10IP TSHZ3 TXLNA TXLNB USHBP1 USP2 ZCCHC10 ZNF148 ZNF250 ZNF774	56 interacting genes: ABI3 AMOTL2 ANKRD33 ATF4 BEX3 BEX5 BFSP1 BICRAL BLOC1S2 C3orf62 CAGE1 CALCOCO1 CCDC153 CCDC183 CDCA4 CDR2L CEP44 CEP63 COPS6 CT55 DISC1 DMAP1 ECSIT HAUS1 HGS KRT14 KRT24 KRT27 KRT31 KRT37 MAGEA6 MBIP MCCD1 MYOG OIP5 PBX2 PBX4 POU6F2 PPP1R13B PSMC5 RINT1 RNASE10 SAPCD2 SCOC SERTAD3 SNAPC5 SNAPIN SUFU SYCE1 SYCE1L TRIB3 USHBP1 USP54 WASHC3 ZNF343 ZNF620
Entrez ID		80254	8419
HPRD ID		07826	04444
Ensembl ID		ENSG00000182923	ENSG00000170819
Uniprot IDs		Q96MT8	Q13515
PDB IDs		6CSU 6CSV
Enriched GO Terms of Interacting Partners?
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