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ZC3H12A and ZC3H12D
Number of citations of the paper that reports this interaction (PubMedID
26134560
)
9
Data Source:
BioGRID
(two hybrid)
ZC3H12A
ZC3H12D
Description
zinc finger CCCH-type containing 12A
zinc finger CCCH-type containing 12D
Image
No pdb structure
GO Annotations
Cellular Component
P-body
Nucleus
Nucleoplasm
Cytoplasm
Rough Endoplasmic Reticulum
Cytoskeleton
Rough Endoplasmic Reticulum Membrane
Protein-containing Complex
Cytoplasmic Ribonucleoprotein Granule
Extrinsic Component Of Endoplasmic Reticulum Membrane
P-body
Nucleus
Nucleoplasm
Cytoplasmic Ribonucleoprotein Granule
Molecular Function
DNA Binding
Chromatin Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Endoribonuclease Activity
Exoribonuclease Activity
Ribonuclease Activity
Thiol-dependent Deubiquitinase
Protein Binding
MiRNA Binding
RNA Stem-loop Binding
MRNA 3'-UTR AU-rich Region Binding
Ribosome Binding
Metal Ion Binding
MRNA Binding
Endoribonuclease Activity
Protein Binding
Metal Ion Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Endonucleolytic Cleavage-dependent Decay
Angiogenesis
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Defense Response To Virus By Host
Immune Response-activating Signal Transduction
Apoptotic Process
Inflammatory Response
Cellular Response To DNA Damage Stimulus
Nervous System Development
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Protein Deubiquitination
Cell Differentiation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Cellular Response To Oxidative Stress
Cellular Response To Glucose Starvation
Positive Regulation Of Protein Import Into Nucleus
Negative Regulation Of Macrophage Activation
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation By Host Of Viral Genome Replication
Negative Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
T Cell Receptor Signaling Pathway
Protein Complex Oligomerization
Defense Response To Virus
Negative Regulation Of Cardiac Muscle Contraction
Positive Regulation Of MRNA Catabolic Process
3'-UTR-mediated MRNA Destabilization
Cellular Response To Lipopolysaccharide
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
RNA Phosphodiester Bond Hydrolysis
RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Cellular Response To Virus
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Execution Phase Of Apoptosis
Positive Regulation Of P38MAPK Cascade
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein Deubiquitination
Negative Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA
Cellular Response To Sodium Arsenite
Cellular Response To Ionomycin
Cellular Response To Chemokine
Negative Regulation Of T-helper 17 Cell Differentiation
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of MiRNA Catabolic Process
MRNA Catabolic Process
3'-UTR-mediated MRNA Destabilization
RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Drugs
Diseases
GWAS
Eyebrow thickness (
26926045
)
Mean corpuscular hemoglobin (
32888494
)
Red cell distribution width (
32888494
)
Asthma (
32296059
)
Dupuytren's disease (
28886342
21732829
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Interacting Genes
19 interacting genes:
AHSP
AIMP2
BTRC
CYFIP2
DNAJB13
EP300
HIF1A
IKBKG
IL6
IRAK2
KPNA2
P4HA3
SHBG
SMAD3
TANK
TRIM55
TRIM63
UBC
ZC3H12D
2 interacting genes:
SYNE1
ZC3H12A
Entrez ID
80149
340152
HPRD ID
08021
19272
Ensembl ID
ENSG00000163874
ENSG00000178199
Uniprot IDs
Q5D1E8
A2A288
PDB IDs
3V32
3V33
3V34
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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