SIKE1 and CBFA2T2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		SIKE1	CBFA2T2
Description		suppressor of IKBKE 1	CBFA2/RUNX1 partner transcriptional co-repressor 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus
	Molecular Function	Protein Binding Protein Kinase Binding Small GTPase Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation
Pathways		TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Triglyceride levels ( 32203549)
Interacting Genes		13 interacting genes: CBFA2T2 CENPQ CTAG1A CTAG1B IKBKE NTAQ1 SCOC STRN3 STX11 TBK1 TXLNA TXLNB ZC2HC1C	34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PHAF1 PRDM14 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652
Entrez ID		80143	9139
HPRD ID		07958	04721
Ensembl ID		ENSG00000052723	ENSG00000078699
Uniprot IDs		Q9BRV8	O43439
PDB IDs		6AKK 6AKL 6AKM
Enriched GO Terms of Interacting Partners?
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