CPSF7 and HINT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CPSF7	HINT1
Description		cleavage and polyadenylation specific factor 7	histidine triad nucleotide binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane	Histone Deacetylase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding Protein Kinase C Binding Protein Binding Hydrolase Activity Adenosine 5'-monophosphoramidase Activity
	Biological Process	Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly	Regulation Of Transcription, DNA-templated Signal Transduction Purine Ribonucleotide Catabolic Process Protein Desumoylation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs RHOBTB1 GTPase cycle
Drugs			Adenosine phosphate Guanosine-5'-Monophosphate 5'-O-(N-Ethyl-Sulfamoyl)Adenosine Adenosine-5'-ditungstate 8-Bromo-Adenosine-5'-Monophosphate
Diseases
GWAS			Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		62 interacting genes: APBB1 ARMC7 ATXN1 CATSPER1 CCDC86 CFAP206 CLK2 CSNK2A1 DVL2 EPM2AIP1 EWSR1 GAS8 GCC1 GRB2 GUCD1 HINT1 HNRNPF ITCH LENG8 LNX1 MAILR MIR1-1 MIR1-2 MIR10B MIR128-2 MIR141 MIR155 MIR16-1 MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR25 MIR29C MIR34B MIR7-1 MIR9-2 MIR93 MIRLET7B NCK2 NUDT21 OGT PATZ1 PID1 PRKAA2 PRMT2 RBM10 RUNX1T1 SEC23B SMAD3 SNRNP25 SNX18 SORBS3 SPG21 SRPK2 SUMO2 TLE5 TNS2 U2AF2 WBP4 WWOX	7 interacting genes: ATM CDC16 CPSF7 ERBB3 MITF SP1 TRIM29
Entrez ID		79869	3094
HPRD ID		16906	03204
Ensembl ID		ENSG00000149532	ENSG00000169567
Uniprot IDs		B4DGF8 Q8N684	A0A384NPU2 P49773
PDB IDs		3N9U	1AV5 1KPA 1KPB 1KPC 1KPE 1KPF 3TW2 4EQE 4EQG 4EQH 4ZKL 4ZKV 5ED3 5ED6 5EMT 5I2E 5I2F 5IPB 5IPC 5IPD 5IPE 5KLY 5KLZ 5KM0 5KM1 5KM2 5KM3 5KM4 5KM6 5KMA 5KMB 5KMC 5O8I 5WA8 5WA9 5WAA 6B42 6G9Z 6J53 6J58 6J5S 6J5Z 6J64 6J65 6N3V 6N3W 6N3X 6N3Y 6YQM
Enriched GO Terms of Interacting Partners?
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