MTERF1 and DCTN1

Number of citations of the paper that reports this interaction (PubMedID 20195357)
31

Data Source:
BioGRID (pull down)

		MTERF1	DCTN1
Description		mitochondrial transcription termination factor 1	dynactin subunit 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid	Kinetochore Spindle Pole Nucleus Nuclear Envelope Cytoplasm Centrosome Centriole Spindle Cytosol Microtubule Microtubule Associated Complex Cell Cortex Microtubule Cytoskeleton Membrane Dynein Complex Axon Microtubule Plus-end Neuron Projection Neuronal Cell Body Intercellular Bridge Mitotic Spindle Cell Cortex Region Centriolar Subdistal Appendage
	Molecular Function	Nucleic Acid Binding Double-stranded DNA Binding RNA Binding Protein Binding	Protein Binding Microtubule Binding Tubulin Binding Protein Kinase Binding Tau Protein Binding Microtubule Plus-end Binding
	Biological Process	DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Termination Of Mitochondrial Transcription DNA Geometric Change	Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Nuclear Migration Nervous System Development Neuromuscular Junction Development Centriole-centriole Cohesion Ventral Spinal Cord Development Positive Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Retrograde Transport, Endosome To Golgi Neuromuscular Process Nuclear Membrane Disassembly Cell Division Regulation Of Mitotic Spindle Organization Motor Behavior Neuron Cellular Homeostasis Positive Regulation Of Microtubule Nucleation Axonal Transport Maintenance Of Synapse Structure Positive Regulation Of Neuromuscular Junction Development Non-motile Cilium Assembly Neuron Projection Maintenance
Pathways		Mitochondrial transcription termination Transcriptional activation of mitochondrial biogenesis	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Hemoglobin levels ( 32327693)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: DCTN1 DNAJC21 EXOC6B SET SGCE SYTL2 TMEM128	51 interacting genes: ACTR1A ACTR1B AKT1 APEX1 BBS1 BBS4 BICD1 BICD2 CASP2 CASP3 CASP7 CDC37 CLIP1 DCTN3 DISC1 DST DTNBP1 DYNC1I2 ENO3 FBXL5 FXR1 GRB2 GSK3B HAP1 HOXA1 HSPB2 KIAA0408 KIF11 KMT2A KRT5 MAP2K3 MAP2K6 MAPRE1 MED14 MTERF1 NEK2 NOD2 PAFAH1B1 PFDN1 PGAM1 PPP1CA RAB6A RBL2 RPGR SEC23A SPTBN2 STAT1 TMED5 TP53RK VIM ZNF512B
Entrez ID		7978	1639
HPRD ID		08373	07206
Ensembl ID		ENSG00000127989	ENSG00000204843
Uniprot IDs		B4DPR9 Q99551	Q14203 Q6MZZ3
PDB IDs		3MVA 3MVB 3N6S 3N7Q 5CKY 5CO0 5CRJ 5CRK	1TXQ 2COY 2HKN 2HKQ 2HL3 2HL5 2HQH 3E2U 3TQ7
Enriched GO Terms of Interacting Partners?
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