MAFK and BACH1

Number of citations of the paper that reports this interaction (PubMedID 26496610)
430

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)
HPRD (in vitro, two hybrid)

		MAFK	BACH1
Description		MAF bZIP transcription factor K	BTB domain and CNC homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coregulator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding RING-like Zinc Finger Domain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Heme Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Nervous System Development	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways		Regulation of HMOX1 expression and activity Heme signaling Regulation of BACH1 activity Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production	Regulation of HMOX1 expression and activity Heme signaling Regulation of BACH1 activity
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Creatine kinase levels ( 29403010) Haemorrhoidal disease ( 33888516) Pancreatic cancer ( 22158540) Selective IgA deficiency ( 27723758) Visceral fat ( 22589738)
Interacting Genes		11 interacting genes: BACH1 BACH2 DNMT3L HIF1A HOXD12 KAT6A MARS1 NFE2 NFE2L1 NFE2L2 NFE2L3	10 interacting genes: ANAPC5 ATF2 DDIT3 HLCS HMMR MAFB MAFK PATZ1 RBCK1 TCF4
Entrez ID		7975	571
HPRD ID		02561	04127
Ensembl ID		ENSG00000198517	ENSG00000156273
Uniprot IDs		A0A024R804 O60675	O14867
PDB IDs			2IHC
Enriched GO Terms of Interacting Partners?
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