CLIP4 and CDK5RAP2

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		CLIP4	CDK5RAP2
Description		CAP-Gly domain containing linker protein family member 4	CDK5 regulatory subunit associated protein 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Plus-end Intracellular Membrane-bounded Organelle	Pericentriolar Material Spindle Pole Cytoplasm Golgi Apparatus Centrosome Cytosol Cytoskeleton Microtubule Cell Junction Microtubule Plus-end Perinuclear Region Of Cytoplasm Extracellular Exosome Mitotic Spindle Pole
	Molecular Function	Protein Binding Microtubule Plus-end Binding	Transcription Cis-regulatory Region Binding Protein Binding Calmodulin Binding Microtubule Binding Tubulin Binding Protein Kinase Binding Gamma-tubulin Binding
	Biological Process	Cytoplasmic Microtubule Organization	Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Chromosome Segregation Centrosome Cycle Centriole Replication Brain Development Neurogenesis Microtubule Organizing Center Organization Positive Regulation Of Microtubule Polymerization Regulation Of Neuron Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Centriole Replication Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Asthma ( 27611488) Height ( 28552196) Photic sneeze reflex ( 27182965) Response to statin therapy ( 20339536) Rheumatoid arthritis ( 24782177)
Interacting Genes		37 interacting genes: APP CDK5RAP2 CLIP1 CMYA5 DCAF6 DES DST GLP1R HSF2BP JAKMIP2 KIF1B KIFC3 LZTS2 MAGEA12 MAP7 MAP7D1 MEOX2 MYBPC1 MYH3 PCARE PDE4DIP PEG10 SIX2 SON SPDYA TACC3 TAF1 TNNT1 TNNT3 TOGARAM2 TPM1 TRIM32 TRIP13 TRMT61B TTN TULP3 ZNF114	27 interacting genes: ABCA2 CDK5 CDK5R1 CLIP4 CRMP1 EEF1G ERG28 FBXO25 HAP1 KAT5 LUC7L2 MAGEH1 MAPRE1 MRRF NEFL PCBD1 PHF19 PTN RBM48 REPS2 SENP2 STARD9 STK36 TBC1D4 TRIM37 TSNAX ZPR1
Entrez ID		79745	55755
HPRD ID		08634	09740
Ensembl ID		ENSG00000115295	ENSG00000136861
Uniprot IDs		A8K6D0 B7Z936 Q8N3C7	A0A0A0MRG9 B3KVI2 B9EG74 Q7Z3M0 Q96SN8
PDB IDs		2Z0W	6X0V
Enriched GO Terms of Interacting Partners?
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