CDK5RAP2 and LUC7L2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		CDK5RAP2	LUC7L2
Description		CDK5 regulatory subunit associated protein 2	LUC7 like 2, pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Spindle Pole Cytoplasm Golgi Apparatus Centrosome Cytosol Cytoskeleton Microtubule Cell Junction Microtubule Plus-end Perinuclear Region Of Cytoplasm Extracellular Exosome Mitotic Spindle Pole	U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Calmodulin Binding Microtubule Binding Tubulin Binding Protein Kinase Binding Gamma-tubulin Binding	RNA Binding MRNA Binding Protein Binding Enzyme Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Chromosome Segregation Centrosome Cycle Centriole Replication Brain Development Neurogenesis Microtubule Organizing Center Organization Positive Regulation Of Microtubule Polymerization Regulation Of Neuron Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Centriole Replication Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint	MRNA Splice Site Selection
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Asthma ( 27611488) Height ( 28552196) Photic sneeze reflex ( 27182965) Response to statin therapy ( 20339536) Rheumatoid arthritis ( 24782177)	Diisocyanate-induced asthma ( 25918132) Left ventricular end-diastolic volume (MTAG) ( 33495596) Left ventricular end-systolic volume (MTAG) ( 33495596)
Interacting Genes		27 interacting genes: ABCA2 CDK5 CDK5R1 CLIP4 CRMP1 EEF1G ERG28 FBXO25 HAP1 KAT5 LUC7L2 MAGEH1 MAPRE1 MRRF NEFL PCBD1 PHF19 PTN RBM48 REPS2 SENP2 STARD9 STK36 TBC1D4 TRIM37 TSNAX ZPR1	58 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 HOXA1 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 OGT PABPC4 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRRM4 SRSF6 SRSF7 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10 ZRSR2
Entrez ID		55755	51631
HPRD ID		09740	17456
Ensembl ID		ENSG00000136861	ENSG00000146963
Uniprot IDs		A0A0A0MRG9 B3KVI2 B9EG74 Q7Z3M0 Q96SN8	Q9Y383
PDB IDs		6X0V
Enriched GO Terms of Interacting Partners?
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