ANKRD55 and CFAP206

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ANKRD55	CFAP206
Description		ankyrin repeat domain 55	cilia and flagella associated protein 206
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Radial Spoke Axoneme Motile Cilium Ciliary Basal Body A Axonemal Microtubule
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Cilium Movement Regulation Of Cilium Beat Frequency Sperm Axoneme Assembly Axoneme Assembly Regulation Of Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Alzheimer's disease (cognitive decline) ( 23535033) Celiac disease or Rheumatoid arthritis ( 21383967) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Fasting insulin ( 33402679) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) IgA levels ( 28628107) IgG glycosylation ( 23382691) Immature fraction of reticulocytes ( 32888494) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Lung function (FEV1) ( 30061609) Macular thickness ( 30535121) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244 24076602 27386562) Optic disc size ( 31809533) Pediatric autoimmune diseases ( 26301688) Post-traumatic stress disorder ( 27167565) Reticulocyte fraction of red cells ( 32888494) Rheumatoid arthritis ( 30423114 30572963 23143596 24390342 20453842) Rheumatoid arthritis (ACPA-negative) ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Sero-negative rheumatoid arthritis ( 28706201) Serum alkaline phosphatase levels ( 33547301) Triglycerides ( 20686565) Type 1 diabetes ( 34127860) Type 2 diabetes ( 27189021 22885922 26961502 29358691 30297969 26818947 32499647 30718926 28869590) Urate levels ( 23263486) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		24 interacting genes: ABI2 ANKS1A BACH2 BANP BOLA2 BOLA2B CABP5 CFAP206 CLIC3 FHL2 FHL5 FRS3 HGS HSF2BP NCK2 NOXA1 PFDN5 PTK6 SETD9 SNX18 TEKT4 TRIM23 ZMYND19 ZSCAN1	64 interacting genes: ADAMTSL4 ANKRD55 APIP ATPAF2 BANP BLZF1 C1orf94 C9orf153 CCDC33 CDX2 CEP57L1 CFP CPSF7 CRX CYSRT1 DISC1 EIF4ENIF1 GFAP GLYR1 GPRASP2 GSE1 HOMEZ IHO1 IKZF3 KIAA1328 KLHL3 KRT31 KRT34 KRT40 KRT75 KRT76 KRTAP13-1 KRTAP26-1 LZTS2 MAGED1 MDFI MEOX2 MIF4GD NME4 PIH1D2 PRDM16 PSMA1 PSMC5 REL RNF138 ROCK1 SAMD3 SAXO1 SORBS3 SOX30 TADA2B TASOR2 TCF12 TEKT1 TFIP11 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 VPS52 ZBTB32 ZNF511
Entrez ID		79722	154313
HPRD ID		07758	12863
Ensembl ID		ENSG00000164512	ENSG00000272514
Uniprot IDs		Q3KP44	Q8IYR0 Q8N771
PDB IDs
Enriched GO Terms of Interacting Partners?
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