NLRX1 and TMPRSS4

		NLRX1	TMPRSS4
Description		NLR family member X1	transmembrane serine protease 4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Plasma Membrane Cell Junction	Extracellular Space Plasma Membrane Integral Component Of Membrane Secretory Granule
	Molecular Function	Protein Binding ATP Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity
	Biological Process	Negative Regulation Of Interferon-beta Production Negative Regulation Of Interleukin-6 Production Intracellular Signal Transduction Negative Regulation Of RIG-I Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Inflammatory Response	Proteolysis Endocytosis Response To Wounding Regulation Of Gene Expression Protein Processing Negative Regulation Of Growth Rate Positive Regulation Of Viral Entry Into Host Cell
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)
Interacting Genes		9 interacting genes: ABCG4 BUD13 C1QTNF5 IFT46 PDZD3 SARM1 SCN3B TMEM25 TMPRSS4	15 interacting genes: BNIP3L CLEC7A CLRN1 ERVFRD-1 FAM209A FNDC9 GPX8 KASH5 LMNA NLRX1 RASGRP4 SIGLEC12 SUSD3 SYNE4 TMEM79
Entrez ID		79671	56649
HPRD ID		17640	05952
Ensembl ID		ENSG00000160703	ENSG00000137648
Uniprot IDs		Q86UT6	B7Z458 B7Z8X1 B7Z900 Q9NRS4
PDB IDs		3UN9
Enriched GO Terms of Interacting Partners?
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