C11orf49 and GSR

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		C11orf49	GSR
Description		chromosome 11 open reading frame 49	glutathione-disulfide reductase
Image		No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Matrix Cytosol External Side Of Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Glutathione-disulfide Reductase (NADPH) Activity Electron Transfer Activity Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process		Glutathione Metabolic Process Electron Transport Chain Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways
Drugs			Glutathione NADH Carmustine 3,6-dihydroxy-xanthene-9-propionic acid 3-sulfino-L-alanine Glutathionylspermidine disulfide 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol Flavin adenine dinucleotide Glutathione disulfide 3-nitro-L-tyrosine 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID Cannabidiol Copper Medical Cannabis Nabiximols
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) D-dimer levels ( 21502573) HDL cholesterol levels ( 32203549) Hip index ( 34021172) Intraocular pressure ( 29617998) Neurociticism ( 29500382)
Interacting Genes		19 interacting genes: ARHGEF15 CDC16 ENY2 FH GCA GSR PHF1 PNMA5 PRKAR1A PSMA1 RAB17 RAB29 RBM48 RPL8 RPS3A TXN2 UBE3A UBQLN4 ZFHX3	4 interacting genes: C11orf49 CDC42 OCM2 PJA1
Entrez ID		79096	2936
HPRD ID		08332	00704
Ensembl ID		ENSG00000149179	ENSG00000104687
Uniprot IDs		B4DUV7 Q9H6J7	P00390 V9HW90
PDB IDs			1ALG 1BWC 1DNC 1GRA 1GRB 1GRE 1GRF 1GRG 1GRH 1GRT 1GSN 1K4Q 1XAN 2AAQ 2GH5 2GRT 3DJG 3DJJ 3DK4 3DK8 3DK9 3GRS 3GRT 3SQP 4GR1 4GRT 5GRT
Enriched GO Terms of Interacting Partners?
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