PRDM2 and BBS5

		PRDM2	BBS5
Description		PR/SET domain 2	Bardet-Biedl syndrome 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus	Cytosol Axoneme Centriolar Satellite BBSome Ciliary Basal Body Ciliary Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Zinc Ion Binding Histone Methyltransferase Activity Sequence-specific DNA Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Determination Of Adult Lifespan Regulation Of Gene Expression Histone Methylation Positive Regulation Of Transcription By RNA Polymerase II	Heart Looping Visual Perception Protein Transport Melanosome Transport Motile Cilium Assembly Intracellular Transport Response To Stimulus Cilium Assembly
Pathways			BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Anti-drug antibodies in autoimmune disease (time to event) ( 33125391) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronotype ( 30696823) Copper levels ( 26025379) HDL cholesterol levels in HIV infection ( 33109212) Intracranial aneurysm ( 30823506) Left ventricular function change in anthracycline treatment ( 28542097) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Parkinson's disease ( 26227905) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Refractive error ( 32231278) Schizophrenia x sex interaction ( 34099189)	Iris heterochromicity ( 30895295)
Interacting Genes		9 interacting genes: BBS5 E2F1 ESR1 H3-4 H3C1 MDM2 PDPN RB1 TBCE	13 interacting genes: CFAP210 COTL1 CRADD CTSK EIF4EBP3 HRH1 KLC3 KLHL23 KLHL41 ORM2 PRDM2 SLC6A15 UBR3
Entrez ID		7799	129880
HPRD ID		03120	10353
Ensembl ID		ENSG00000116731	ENSG00000163093
Uniprot IDs		Q13029	A0A0S2Z626 Q8N3I7
PDB IDs		2JV0 2QPW	6XTB
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?