PRDM2 and PDPN

		PRDM2	PDPN
Description		PR/SET domain 2	podoplanin
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus	Ruffle Mitochondrion Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Cell Junction Filopodium Lamellipodium Membrane Cytoplasmic Vesicle Filopodium Membrane Microvillus Membrane Ruffle Membrane Cell Projection Membrane Raft Leading Edge Of Lamellipodium Tetraspanin-enriched Microdomain
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Zinc Ion Binding Histone Methyltransferase Activity Sequence-specific DNA Binding	Signaling Receptor Binding Water Transmembrane Transporter Activity Protein Binding Folic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Water Channel Activity Chemokine Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Determination Of Adult Lifespan Regulation Of Gene Expression Histone Methylation Positive Regulation Of Transcription By RNA Polymerase II	Cell Morphogenesis Lymphangiogenesis Water Transport Amino Acid Transport Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Regulation Of Cell Shape Positive Regulation Of Epithelial To Mesenchymal Transition Folic Acid Transport Platelet Activation Lung Development Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Wound Healing, Spreading Of Cells Lymph Node Development Positive Regulation Of Cellular Component Movement Response To Hyperoxia Lymphatic Endothelial Cell Fate Commitment Actin-mediated Cell Contraction Positive Regulation Of Extracellular Matrix Disassembly Cell-cell Adhesion Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Platelet Aggregation Regulation Of Myofibroblast Contraction Regulation Of Lamellipodium Morphogenesis
Pathways			GPVI-mediated activation cascade
Drugs
Diseases
GWAS		Anti-drug antibodies in autoimmune disease (time to event) ( 33125391) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronotype ( 30696823) Copper levels ( 26025379) HDL cholesterol levels in HIV infection ( 33109212) Intracranial aneurysm ( 30823506) Left ventricular function change in anthracycline treatment ( 28542097) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Parkinson's disease ( 26227905) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Refractive error ( 32231278) Schizophrenia x sex interaction ( 34099189)
Interacting Genes		9 interacting genes: BBS5 E2F1 ESR1 H3-4 H3C1 MDM2 PDPN RB1 TBCE	7 interacting genes: CELA2B LHX1 PRDM2 PRMT1 TMEM14B TOM1L1 ZBTB48
Entrez ID		7799	10630
HPRD ID		03120	16398
Ensembl ID		ENSG00000116731	ENSG00000162493
Uniprot IDs		Q13029	Q86YL7
PDB IDs		2JV0 2QPW	3WSR 4YO0 5XCV 7C94
Enriched GO Terms of Interacting Partners?
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