SLC30A3 and ELOVL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC30A3	ELOVL4
Description		solute carrier family 30 member 3	ELOVL fatty acid elongase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endosome Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Synaptic Vesicle Membrane Late Endosome Membrane Neuron Projection Hippocampal Mossy Fiber Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse	Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding	Protein Binding G Protein-coupled Photoreceptor Activity Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Response To Zinc Ion Positive Regulation Of Transport Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle	Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Detection Of Visible Light Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways		Zinc efflux and compartmentalization by the SLC30 family	Synthesis of very long-chain fatty acyl-CoAs
Drugs			Omega-3-carboxylic acids
Diseases
GWAS		Metabolite levels ( 23823483)	Aging ( 22773346) Body mass index ( 23669352) Chronic obstructive pulmonary disease ( 28166215) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Macular thickness ( 30535121) Partial epilepsies ( 20522523) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		28 interacting genes: AP3B1 AP3D1 AP3S1 CD40 CGRRF1 DNAJC5 ELOVL4 FCRL3 GJA8 GOLM1 GPR152 GPR42 GPX8 HSD17B13 LMNA NAALADL2 OCIAD1 RETREG3 RNF19B RTN3 SCN3B SGPL1 SLC10A6 SLC30A8 SLC34A2 SLC35C2 TMEM14B TMEM242	95 interacting genes: ADGRE2 ANKRD46 APOL3 ATP13A1 BCL2L1 BET1 BIK BNIP1 BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD70 CLCA4 CLDND2 CMTM3 CMTM5 CMTM7 COL4A5 CYB5R3 CYP4F2 ERG28 FA2H FAM177A1 FAM3C FAXDC2 FDFT1 FKBP8 FXYD6 GIMAP1 GIMAP5 GOSR2 GPR37L1 GYPA HMOX1 HMOX2 HSD3B7 IER3IP1 ITGAM JAGN1 LEPROTL1 LHFPL5 LY6D MALL MMP14 NINJ2 ORMDL2 ORMDL3 PKMYT1 PLLP PLN PLP1 PTPN1 RAB18 RTP2 SEC22A SEC22B SERF1A SERF1B SERP2 SFT2D2 SLC30A3 SLC30A8 SNORC STX3 SYNDIG1 TECR TF TMEM11 TMEM128 TMEM19 TMEM199 TMEM203 TMEM218 TMEM222 TMEM242 TMEM243 TMEM254 TMEM42 TMEM44 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 VAMP1 VAMP3 VAMP4 VAMP5 VAPB YIF1A YIPF6 ZDHHC21 ZFPL1
Entrez ID		7781	6785
HPRD ID		11924	05697
Ensembl ID		ENSG00000115194	ENSG00000118402
Uniprot IDs		B4DXX8 Q99726	Q9GZR5
PDB IDs
Enriched GO Terms of Interacting Partners?
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