TRIM26 and RABEP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TRIM26	RABEP1
Description		tripartite motif containing 26	rabaptin, RAB GTPase binding effector protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytoplasm Cytosol	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Regulation Of Catalytic Activity Membrane Fusion Protein Localization To Ciliary Membrane
Pathways		Interferon gamma signaling	TBC/RABGAPs
Drugs
Diseases
GWAS		Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Hematocrit ( 32888494) LDL cholesterol levels ( 32203549) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 21926974 22883433 30285260) Squamous cell lung carcinoma ( 28604730) Triglyceride levels ( 32203549) Waist-hip index ( 34021172)	Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		28 interacting genes: BEND7 BIVM DDX41 EPN2 EPN3 INCA1 IRF3 LMNA MACROH2A1 MAGEA6 MIR138-2 MIR18B MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 SUMO2 THAP1 TLE5 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5	59 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 DDX3X ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774
Entrez ID		7726	9135
HPRD ID		02901	04684
Ensembl ID		ENSG00000234127	ENSG00000029725
Uniprot IDs		A0A024RCP3 Q12899	B4DMM4 Q15276
PDB IDs			1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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