TMEM50B and AMIGO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM50B	AMIGO1
Description		transmembrane protein 50B	adhesion molecule with Ig like domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket
	Molecular Function	Molecular_function Protein Binding	Protein Binding Potassium Channel Regulator Activity
	Biological Process	Biological_process Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23128233) Educational attainment ( 25201988)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		22 interacting genes: AMIGO1 BCL2L1 CLRN1 CREB3L1 CYP27B1 EDA FAM209A FXYD3 GPR152 GPX8 HLA-DPA1 LEPROTL1 LHFPL5 NCR1 SCN3B SLC10A6 SLC16A13 SLC35C2 TMEM14B TMEM52B TMEM88 TMX2	35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2
Entrez ID		757	57463
HPRD ID		10747	11129
Ensembl ID		ENSG00000142188	ENSG00000181754
Uniprot IDs		P56557	Q86WK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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