ZIC1 and DAPL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZIC1	DAPL1
Description		Zic family member 1	death associated protein like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Death Domain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Central Nervous System Development Brain Development Regulation Of Smoothened Signaling Pathway Cell Differentiation Positive Regulation Of Protein Import Into Nucleus Inner Ear Morphogenesis Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Autophagy Cell Differentiation Cellular Response To Amino Acid Starvation Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chin dimples ( 27182965) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Monobrow ( 27182965) Multiple sclerosis ( 19010793) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Alzheimer's disease in APOE e4+ carriers ( 25778476) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Obesity-related traits ( 23251661)
Interacting Genes		71 interacting genes: ABHD11 ANKRD10 ARID5A ATP23 BBS4 C11orf1 CDPF1 CRX CYSRT1 DAPL1 EEF1AKMT3 FAM168B FOXH1 GLI1 GLI2 GLI3 INTS11 KLHL26 KRT31 KRT34 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LITAF MAGED1 METTL27 MGAT5B NFKBID OIP5 OXER1 PATZ1 PEF1 PLAAT1 PLSCR3 RBPMS REL RFC2 RNF144B RUSC1 SMAD4 SMUG1 SPAG8 SPATS1 SUFU TBX19 TEPSIN TLE5 TRAF1 TRIP6 TSC1 UBE2I UFSP1 WWOX YPEL3 ZNF34 ZNF474 ZNF620	7 interacting genes: FHL2 FNDC3B LSM1 TRIM55 TRIM63 TSR2 ZIC1
Entrez ID		7545	92196
HPRD ID		02718	18709
Ensembl ID		ENSG00000152977	ENSG00000163331
Uniprot IDs		Q15915	A0PJW8 M1E9T5
PDB IDs
Enriched GO Terms of Interacting Partners?
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