ZIC1 and ZNF474

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZIC1	ZNF474
Description		Zic family member 1	zinc finger protein 474
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Central Nervous System Development Brain Development Regulation Of Smoothened Signaling Pathway Cell Differentiation Positive Regulation Of Protein Import Into Nucleus Inner Ear Morphogenesis Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chin dimples ( 27182965) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Monobrow ( 27182965) Multiple sclerosis ( 19010793) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Intraocular pressure ( 29617998)
Interacting Genes		71 interacting genes: ABHD11 ANKRD10 ARID5A ATP23 BBS4 C11orf1 CDPF1 CRX CYSRT1 DAPL1 EEF1AKMT3 FAM168B FOXH1 GLI1 GLI2 GLI3 INTS11 KLHL26 KRT31 KRT34 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LITAF MAGED1 METTL27 MGAT5B NFKBID OIP5 OXER1 PATZ1 PEF1 PLAAT1 PLSCR3 RBPMS REL RFC2 RNF144B RUSC1 SMAD4 SMUG1 SPAG8 SPATS1 SUFU TBX19 TEPSIN TLE5 TRAF1 TRIP6 TSC1 UBE2I UFSP1 WWOX YPEL3 ZNF34 ZNF474 ZNF620	29 interacting genes: ABI2 ATP6V0D2 BANP C2CD6 CABP5 CCDC57 COMMD8 CPNE7 CTNNA3 FRMD8 GPATCH11 GRB2 GYS1 IL16 KCTD7 MCMBP MLH1 NOXA1 PFKFB1 PPL PRKAB2 RSPH14 SEPHS1 TCF19 TEKT4 TRIM23 TSR2 UBASH3A ZIC1
Entrez ID		7545	133923
HPRD ID		02718	13411
Ensembl ID		ENSG00000152977	ENSG00000164185
Uniprot IDs		Q15915	Q6S9Z5
PDB IDs
Enriched GO Terms of Interacting Partners?
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