ZBTB14 and RPS25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZBTB14	RPS25
Description		zinc finger and BTB domain containing 14	ribosomal protein S25
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome	Nucleus Nucleoplasm Nucleolus Cytosol Ribosome Postsynaptic Density Small Ribosomal Subunit Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development	Cytoplasmic Translation RRNA Processing Translation Ribosomal Small Subunit Biogenesis
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)
Interacting Genes		60 interacting genes: AP1M1 AP4B1 ASXL3 ATP5PO ATRIP B4GALT6 BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 COLEC12 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 ITGB7 KAT5 KCNAB3 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PLAGL1 PNKP POLR2L PRMT1 PTPN2 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SLC4A1 SNRPB2 SYT16 TCEANC TM9SF1 TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2	15 interacting genes: APP DUX4 HAP1 HMBOX1 HOMEZ NKAPD1 PTEN SC5D SGSM2 SLC26A4-AS1 STAC3 THAP1 TSPYL2 UPF2 ZBTB14
Entrez ID		7541	6230
HPRD ID		03674	01593
Ensembl ID		ENSG00000198081	ENSG00000118181
Uniprot IDs		B2R850 O43829	P62851
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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