ZBTB14 and AP4B1

		ZBTB14	AP4B1
Description		zinc finger and BTB domain containing 14	adaptor related protein complex 4 subunit beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome	Trans-Golgi Network Cytosol Extrinsic Component Of Membrane AP-4 Adaptor Complex Clathrin Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Clathrin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development	Protein Targeting Protein Localization Vesicle-mediated Transport
Pathways			Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)	Alopecia areata ( 25608926) Breast cancer ( 23535729) Crohn's disease ( 28067908) Mean corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)
Interacting Genes		60 interacting genes: AP1M1 AP4B1 ASXL3 ATP5PO ATRIP B4GALT6 BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 COLEC12 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 ITGB7 KAT5 KCNAB3 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PLAGL1 PNKP POLR2L PRMT1 PTPN2 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SLC4A1 SNRPB2 SYT16 TCEANC TM9SF1 TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2	8 interacting genes: AP4E1 AP4M1 BMP10 BUB1 BUB1B TEPSIN ZBTB14 ZNF576
Entrez ID		7541	10717
HPRD ID		03674	06259
Ensembl ID		ENSG00000198081	ENSG00000134262
Uniprot IDs		B2R850 O43829	A0A024R0J5 B1ALD0 B3KSJ4 B4DTG3 Q9Y6B7
PDB IDs			2MJ7
Enriched GO Terms of Interacting Partners?
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