SF1 and RBM7

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid)

		SF1	RBM7
Description		splicing factor 1	RNA binding motif protein 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome Nuclear Body	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding	RNA Binding Single-stranded RNA Binding Protein Binding SnRNA Binding 14-3-3 Protein Binding Pre-mRNA Intronic Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Male Sex Determination Nuclear Body Organization Leydig Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome SnRNA Catabolic Process Meiotic Cell Cycle
Pathways		mRNA Splicing - Major Pathway
Drugs		Artenimol
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Urate levels ( 21768215)	Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		60 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CDC42 CIAO1 DDX17 DUX4L9 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MIR106B MIR155 MIR19B2 MIR34A MIRLET7G MKRN3 NCK2 NFKB1 OGT OSTF1 PLSCR1 PRKG1 PRPF40A PSMA3 PUF60 RBM10 RBM17 RBM4 RBM7 RBPMS SEC23A SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TNPO2 TRIM23 TRIM69 TTN TXNL4B U2AF2 UBL5 VEGFB WBP4 WDR77 WDR83 WWP2 ZNF461	15 interacting genes: CCDC85B CCDC88B CHERP DHX8 EVI5L HMG20A HNRNPK HYOU1 KHDRBS1 KHDRBS3 RBM4 RBMX SF1 SF3B2 SRSF3
Entrez ID		7536	10179
HPRD ID		03306	11488
Ensembl ID		ENSG00000168066	ENSG00000076053
Uniprot IDs		A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637	G3V1T9 J3KPD3 Q9Y580
PDB IDs		1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX	2M8H 5IQQ 5LXR 5LXY
Enriched GO Terms of Interacting Partners?
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