YWHAE and SYN2

  • Number of citations of the paper that reports this interaction (PubMedID 10358015)
  • 31
  • Data Source:
  • BioGRID (two hybrid)

YWHAE

SYN2

Description tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon synapsin II
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body shape index ( 34021172)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Circulating leptin levels or type 2 diabetes ( 32341051)
  • Creatinine levels ( 29403010)
  • Eosinophil counts ( 32888494)
  • Estimated glomerular filtration rate ( 31152163)
  • Fasting blood insulin (BMI interaction) ( 22581228)
  • Glomerular filtration rate ( 29403010)
  • Glycated hemoglobin levels ( 34059833 28898252)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Leprosy ( 27976721)
  • Nontraumatic osteonecrosis of the femoral head ( 32701715)
  • Platelet count ( 22139419 29403010)
  • Thyroid stimulating hormone levels ( 32769997 25743335)
  • Triglycerides ( 30275531)
  • Type 2 diabetes ( 18372903)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 148 interacting genes: - ABL1 ACD AKAP13 AKAP9 ANKHD1-EIF4EBP3 ANKZF1 ARHGEF2 ARHGEF28 ATP6V0B ATXN1 BAD BCR BEX3 CALM1 CAP2 CASK CASP3 CCDC125 CCR9 CDC25A CDC25B CDK11B CDK14 CDK16 CDKN1B CEP131 CEP95 CGNL1 CHAF1A CHST11 CYSLTR2 DDX54 DISC1 DYRK1A ENKD1 EXO1 FAM13B FAM53C FGF12 FHL1 FTH1 GAPDH GPRIN2 GRAP2 GSTA1 GSTM3 GTF2B HDAC4 HDAC5 HIVEP2 HNRNPC HSF1 HSP90AA1 HSPB1 IGF1R IL7R ING1 IRAG2 IRS1 IRS2 ITPRID2 KANK1 KCNH2 KCNK15 KCNK3 KCNK9 KIAA0232 KIF1C KLC4 KRT18 LCP2 MAGEB4 MAP3K1 MAP3K10 MAP3K2 MAP3K3 MAP3K5 MAPK7 MCM10 MDM4 METAP2 MSL2 MST1R MT-CO2 MYH10 NAF1 NCOR2 NDEL1 NIN PAPOLA PARD3B PCM1 PIMREG PNLIP POT1 PRC1 PRDX6 PRKCG RAB11FIP2 RAF1 RAP1GAP2 RASAL3 RASGRF1 RBIS RBM14 REM1 RGS3 RIN1 RPA2 RPGR RXFP3 SAMSN1 SH3BP4 SLC8A1 SLC8A2 SLC8A3 SMAGP SNAPIN SNCA SNF8 SORBS2 SRC SYN2 TAF7 TAFAZZIN TBC1D3F TBP TCEANC TFDP2 TGFB1 TLK1 TNFAIP3 TOP2A TSC1 TSC2 UBE3A USP43 VIM WNK1 WWTR1 YWHAB YWHAG YWHAH YWHAQ YWHAZ ZC3HC1 ZNF839 7 interacting genes: CHRM4 NOS1AP PRKACA SYN1 SYN3 YWHAE YWHAZ
Entrez ID 7531 6854
HPRD ID 05457 02857
Ensembl ID ENSG00000108953 ENSG00000157152
Uniprot IDs P62258 V9HW98 B3KRB3 Q59GM1 Q86VA8 Q92777
PDB IDs 2BR9 3UAL 3UBW 6EIH
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?