LDLRAD4 and ZDHHC22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LDLRAD4	ZDHHC22
Description		low density lipoprotein receptor class A domain containing 4	zinc finger DHHC-type palmitoyltransferase 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane
	Molecular Function	R-SMAD Binding	Protein Binding Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of SMAD Protein Complex Assembly Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation	Protein Targeting To Membrane Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Depressive symptom improvement ( 30468137) Gut microbiota (functional units) ( 27694959) Macular thickness ( 30535121) Plateletcrit ( 32888494) Serum alkaline phosphatase levels ( 33547301)	Cerebrospinal P-tau181p levels ( 28247064) Large artery stroke ( 24262325) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145)
Interacting Genes		3 interacting genes: GET3 SGTA ZDHHC22	15 interacting genes: CD79A CLEC4D CLSTN3 CREB3L1 FCRL2 FNDC9 GPX8 LDLRAD4 PROX2 PVR RPRM TMEM14B TMEM86B TMEM88 TRIM59
Entrez ID		753	283576
HPRD ID		07358	12655
Ensembl ID		ENSG00000168675	ENSG00000177108
Uniprot IDs		A0A7I2V2E6 A0A7I2V575 A8K6A9 O15165	Q8N966
PDB IDs
Enriched GO Terms of Interacting Partners?
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