FMNL1 and HMG20A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FMNL1	HMG20A
Description		formin like 1	high mobility group 20A
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Cortex Membrane Bleb Phagocytic Vesicle Extracellular Exosome	Nucleus
	Molecular Function	Molecular_function Protein Binding Small GTPase Binding GTPase Activating Protein Binding Actin Filament Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Cell Shape Cell Migration Cortical Actin Cytoskeleton Organization Actin Filament Severing	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation
Pathways		RHO GTPases Activate Formins RHO GTPases Activate Formins CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Craniofacial microsomia ( 26853712) Hypothyroidism ( 30367059) Male-pattern baldness ( 28196072) Thyroid stimulating hormone levels ( 30367059)	Fasting glucose ( 33402679 34059833) Glycated hemoglobin levels ( 34059833) Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)
Interacting Genes		11 interacting genes: APP GAS7 HMG20A PFN1 PFN2 PRPF40A RAC1 SRPK2 TCERG1 TRIM54 XRCC6	60 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 CREBBP DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 FXR1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1
Entrez ID		752	10363
HPRD ID		06876	16116
Ensembl ID		ENSG00000184922	ENSG00000140382
Uniprot IDs		O95466	B4DMG1 Q9NP66
PDB IDs		4YDH
Enriched GO Terms of Interacting Partners?
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