HMG20A and DCTN4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		HMG20A	DCTN4
Description		high mobility group 20A	dynactin subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Kinetochore Spindle Pole Stress Fiber Nucleus Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Dynactin Complex Focal Adhesion Cell Cortex Sarcomere
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation
Pathways			MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Fasting glucose ( 33402679 34059833) Glycated hemoglobin levels ( 34059833) Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma ( 28604730)
Interacting Genes		60 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 CREBBP DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 FXR1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1	8 interacting genes: ACTR10 ACTR1A ATP7B CALCOCO2 GOLGA2 HMG20A MTUS2 PNMA1
Entrez ID		10363	51164
HPRD ID		16116	13126
Ensembl ID		ENSG00000140382	ENSG00000132912
Uniprot IDs		B4DMG1 Q9NP66	A0A0S2Z5D4 Q9NSJ5 Q9UJW0
PDB IDs
Enriched GO Terms of Interacting Partners?
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