NELFA and CDK3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NELFA	CDK3
Description		negative elongation factor complex member A	cyclin dependent kinase 3
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body NELF Complex	Nucleus
	Molecular Function	Chromatin Binding Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Multicellular Organism Development Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone H3-K4 Methylation	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Population Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: APP CDK3 MLH1 NCK2 NELFCD NSD2 OPRM1 PIN1 PRR22 SH3KBP1 SIAH1 SMARCD1	41 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCND3 CCNE1 CCNE2 CCNH CCNI CDC37 CDKN1A CDKN1B CDKN3 CKS1B CKS2 E2F1 E2F2 E2F3 FOXJ1 FOXP2 FRS2 KIR3DL1 LHX3 LHX4 MEOX2 NAP1L1 NEDD4L NELFA OR2G6 OTX2 PAX5 PAX6 PAX8 PPARA RACGAP1 RB1 SPDYE4 STN1 TRIM55 TRIM63
Entrez ID		7469	1018
HPRD ID		12080	00446
Ensembl ID		ENSG00000185049	ENSG00000250506
Uniprot IDs		A0A0C4DFX9 Q9H3P2	Q00526
PDB IDs		5L3X 6GML	1LFN
Enriched GO Terms of Interacting Partners?
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