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CDK3 and NELFA
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
CDK3
NELFA
Description
cyclin dependent kinase 3
negative elongation factor complex member A
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Nuclear Body
NELF Complex
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Chromatin Binding
Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Population Proliferation
G0 To G1 Transition
Cell Division
Regulation Of Cell Cycle
Multicellular Organism Development
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Histone H3-K4 Methylation
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Interacting Genes
41 interacting genes:
APP
CABLES1
CABLES2
CCNA2
CCNC
CCND3
CCNE1
CCNE2
CCNH
CCNI
CDC37
CDKN1A
CDKN1B
CDKN3
CKS1B
CKS2
E2F1
E2F2
E2F3
FOXJ1
FOXP2
FRS2
KIR3DL1
LHX3
LHX4
MEOX2
NAP1L1
NEDD4L
NELFA
OR2G6
OTX2
PAX5
PAX6
PAX8
PPARA
RACGAP1
RB1
SPDYE4
STN1
TRIM55
TRIM63
12 interacting genes:
APP
CDK3
MLH1
NCK2
NELFCD
NSD2
OPRM1
PIN1
PRR22
SH3KBP1
SIAH1
SMARCD1
Entrez ID
1018
7469
HPRD ID
00446
12080
Ensembl ID
ENSG00000250506
ENSG00000185049
Uniprot IDs
Q00526
A0A0C4DFX9
Q9H3P2
PDB IDs
1LFN
5L3X
6GML
Enriched GO Terms of Interacting Partners
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