USP1 and PHF7

Number of citations of the paper that reports this interaction (PubMedID 23105109)
19

Data Source:
BioGRID (two hybrid)

		USP1	PHF7
Description		ubiquitin specific peptidase 1	PHD finger protein 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Peptidase Activity	Protein Binding Metal Ion Binding
	Biological Process	Skeletal System Development DNA Repair Regulation Of DNA Repair Ubiquitin-dependent Protein Catabolic Process Response To UV Protein Deubiquitination Monoubiquitinated Protein Deubiquitination DNA Damage Response, Detection Of DNA Damage
Pathways		Recognition of DNA damage by PCNA-containing replication complex Fanconi Anemia Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 26192919 28067908) Lipid traits ( 24386095) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 31589552) Red blood cell count ( 32888494) Regular attendance at a gym or sports club ( 29970889) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 32203549) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872) Triglyceride levels ( 32154731)
Interacting Genes		16 interacting genes: DTX3 EZH2 EZR FANCD2 FANCI KLHDC2 KPNA1 NMRAL1 PCNA PHF7 TRAF6 TRIM46 UBB UBC UBE2K WDR48	18 interacting genes: APP ARIH2 DTX3L FBXL17 H3-4 IKBKG MAGEF1 MDM2 RNF111 RNF14 RNF34 SRPK1 TRIM26 TRIM41 UBE2D2 UBE2D4 USP1 USP15
Entrez ID		7398	51533
HPRD ID		04593	15127
Ensembl ID		ENSG00000162607	ENSG00000010318
Uniprot IDs		O94782	A0A024R336 A8K856 Q9BWX1
PDB IDs		6DO5
Enriched GO Terms of Interacting Partners?
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